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Cheap Flights from Mexico City to Santo Domingo

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Compare Mexico City to Santo Domingo flight deals

Find the cheapest month or even day of the year to fly to Santo Domingo

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Flight deals from Mexico City to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Mexico City to Santo Domingo? Find the lowest prices on one-way and return tickets right here.
Santo Domingo.R 1,998 per passenger.Departing Fri, 12 Dec.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 12 Dec, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 1,998, select.
Santo Domingo.R 2,817 per passenger.Departing Fri, 29 Aug.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 29 Aug, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,817, select.
Santo Domingo.R 2,817 per passenger.Departing Wed, 10 Sep.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Wed, 10 Sep, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,817, select.
Santo Domingo.R 2,827 per passenger.Departing Thu, 13 Nov.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 13 Nov, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,827, select.
Santo Domingo.R 2,829 per passenger.Departing Fri, 3 Oct.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 3 Oct, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,829, select.
Santo Domingo.R 2,829 per passenger.Departing Thu, 19 Jun.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 19 Jun, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,829, select.
Santo Domingo.R 2,882 per passenger.Departing Fri, 9 May.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 9 May, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,882, select.
Santo Domingo.R 2,966 per passenger.Departing Wed, 9 Jul.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Wed, 9 Jul, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,966, select.

Find the cheapest month to fly from Mexico City to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Mexico City to Santo Domingo flights are currently cheapest in December.
Apr
from R 3,330
May
from R 2,882
Jun
from R 2,829
Jul
from R 2,966
Aug
from R 2,817
Sep
from R 2,817
Oct
from R 2,829
Nov
from R 2,827
Dec
from R 1,998
Jan
Find prices
Feb
Find prices
Mar
Find prices

Direct flights from Mexico City to Santo Domingo

Alternative Mexico City to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Mexico City to Santo Domingo? You could fly into the following airports instead.

Mexico City to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight foundR 1,998
Cheapest month to flyDecember
Average flight time4 hrs, 22 mins
Most popular airlineArajet
Average flights per week18

Finding cheap flights from Mexico City to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Mexico City to Santo Domingo is R 4,293. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
4 hours and 22 minutes is the average flight time from Mexico City to Santo Domingo.
Arajet, Aeromexico and World Ticket Ltd fly direct from Mexico City to Santo Domingo.
As of April 2025, there are 18 flights per week flying from Mexico City to Santo Domingo.
The cheapest month to fly from Mexico City to Santo Domingo is usually April 2025.
If you're flying from Mexico City, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from R 4,293.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Mexico City to Santo Domingo on Monday, 24 November 2025.
Yes – the average flight time is 4 hours and 22 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 27°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
The cheapest airline that flies to Santo Domingo is Arajet .

Flying from Mexico City to Santo Domingo: what you need to know

  • Begin planning your holiday by considering where you'll board your flight from Mexico City to Santo Domingo. Benito Juarez International Airport (MEX) and Santa Lucia Air Force Base Airport (NLU) are the main airports in Mexico City.

  • Arrive in Santo Domingo at Las Americas International Airport (SDQ) or Dr. Joaquin Balaguer International Airport (JBQ).

  • Around 4 hours 25 minutes is how long you'll be in transit on a direct Mexico City to Santo Domingo flight.

  • Santo Domingo's timezone is UTC-4, which makes Santo Domingo two hours ahead of Mexico City.

  • Benito Juarez International Airport (MEX) to Las Americas International Airport (SDQ) is the most popular route that connects these two cities. There are seven weekly flights to choose from. If you have things to finalize before heading off, the last flight from Mexico City to Santo Domingo is with Aeromexico at 23:55. Go for the first MEX to SDQ departure with Aeromexico at 00:15 to make the most of your arrival in Santo Domingo.

  • For a stress-free start to your trip, arrive at the airport two hours ahead of international flights and an hour before domestic departures. This ensures you have enough time to board your Mexico City to Santo Domingo flight.

  • Be prepared for longer lines in popular months such as July. Arriving up to four hours in advance for an international flight and two hours for domestic departures will give you plenty of time for security and boarding.

How to find the cheapest flights from Mexico City to Santo Domingo

  • At the moment, R 1,998 is the best price we've found for a one-way ticket from Mexico City to Santo Domingo. The cheapest price for a return flight is R 4,293. Keep in mind fares can change due to demand at the time of booking.

  • Book two months before you want to fly. Research into pricing trends suggests this is the ideal window for finding cheap Mexico City to Santo Domingo flights.

  • Organise your trip for May. That's the best month for scoring an incredible deal on plane tickets from Mexico City to Santo Domingo. If you're flexible with your dates, use the 'Whole month' tool to see the cheapest price across every month.

  • There's no need to search every day to see if prices have dropped when you set up a Price Alert. We'll update you the moment there's a better deal on cheap flights from Mexico City to Santo Domingo.

  • Tailor your flights using filters. Pick your preferred departure and arrival times, total journey duration and airlines. You can also sort your results by 'Fastest,' 'Best' or 'Cheapest' Mexico City to Santo Domingo flights.

Flying from Mexico City

Benito Juarez International Airport (MEX)

  • If you're looking for a direct flight from Mexico City to Santo Domingo, you can leave from Benito Juarez International Airport (MEX). Travel from MEX to Las Americas International Airport (SDQ) in one seamless journey.

  • Be on the lookout for deals with Aeromexico. This airline offers direct Mexico City to Santo Domingo plane tickets out of MEX.

  • Stopovers are the ideal opportunity to take a travel break — and possibly even tour another city. When browsing Mexico City to Santo Domingo flights departing from Benito Juarez International Airport, uncheck the 'Direct flights only' box to see where you can stop along the way. Top options include:

    • Cancun International Airport (CUN)

    • El Salvador International Airport (SAL)

    • Miami International Airport (MIA)

  • MEX is about 6 kilometres from central Mexico City. If you're driving, catching a cab or ride-sharing from the centre, it'll take 25 minutes or so to get there, depending on traffic conditions. If you're taking public transport, expect the trip time to be around 55 minutes.

  • Want a relaxed start to your travels? Stay near Benito Juarez International Airport. Whether you're boarding an early flight from Mexico City to Santo Domingo or just don't like being rushed, these hotels are the answer:

  • Benito Juarez International Airport gets top marks for on-time performance. 80.91% of flights that depart MEX arrive at their destination on time.

Santa Lucia Air Force Base Airport (NLU)

  • You can book a direct flight from Mexico City to Santo Domingo out of Santa Lucia Air Force Base Airport (NLU). Nonstop services from NLU will take you to Las Americas International Airport (SDQ).

  • From NLU, you can book a direct Mexico City to Santo Domingo plane ticket with Arajet.

  • Get more out of your holiday with a stopover on your Mexico City to Santo Domingo flight. Visit friends or family or cross another city off your list. Whatever you want to do, here's where you can stop between Santa Lucia Air Force Base Airport and Santo Domingo:

    • Cancun International Airport (CUN)

    • Tocumen International Airport (PTY)

    • El Dorado International Airport (BOG)

  • You can reach NLU from central Mexico City in about 55 minutes by car, depending on traffic. The ride on public transport takes roughly 1 hour 45 minutes to travel the 32 kilometres or so.

  • Getting to the airport on time before your flight from {"defaultCase":"Mexico City","accusativeCase":"Mexico City","nominativeCase":"Mexico City","dativeCase":"Mexico City"} to Santo Domingo is much simpler when you stay near Santa Lucia Air Force Base Airport. Consider booking a room at Verticca Hotel the night before flying out.

  • 67.58% of all departures from Santa Lucia Air Force Base Airport arrive according to schedule.

Arriving in Santo Domingo

Las Americas International Airport (SDQ)

Dr. Joaquin Balaguer International Airport (JBQ)

  • Dr. Joaquin Balaguer International Airport (JBQ) is about 13 kilometres from central Santo Domingo. After your flight from Mexico City to Santo Domingo, it takes approximately 25 minutes to reach the heart of the city in a ride-share or cab.

  • Unpack your bag and relax not long after your flight from Mexico City to Santo Domingo at Moderno Apartamento Para tu Estancia. This comfortable accommodation option is an easy drive from JBQ.

  • Why base your plans around someone else's schedule? Grab a Dr. Joaquin Balaguer International Airport rental car and stay in control of your journey. Reserve your wheels here with FlexWays.

  • Get the vehicle you prefer, not just what's available, by booking your ride from JBQ in advance. You can also avoid paying extra, especially during peak travel times.

Best time to go to Santo Domingo

  • It's time to work out your travel dates for your flight from Mexico City to Santo Domingo. January is the busiest month for a trip to Santo Domingo. If you like a more peaceful vibe, go in May.

  • Lock in a Mexico City to Santo Domingo ticket departing in September if you want to explore the city during its warmest month. You can expect temperatures in Santo Domingo to range from 23ºC (73ºF) to 33ºC (91ºF).

  • Look for cheap flights from Mexico City to Santo Domingo in February if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between 19ºC (66ºF) and 29ºC (84ºF) on average.

More about Santo Domingo

  • Start your Santo Domingo trip off on the right foot by choosing the perfect place to stay. As soon as you've booked your flight from Mexico City to Santo Domingo, explore our range of accommodation options including:

  • All great holidays should include a little sightseeing. Alcazar de Colon, National Pantheon (Pantheon Nacional) and National Palace are must-visits when exploring Santo Domingo.

Explore more of Dominican Republic

  • Santo Domingo is always a good idea, but there are so many other corners of Dominican Republic you'll want to see. Around 13 kilometres east of Santo Domingo, a visit to Santo Domingo Este will keep your itinerary busy. Don't miss top attractions like Museo Las Tres Aves, billeteros Park and Abuela Mota Final Resting Place.

  • Around 64 kilometres east of Santo Domingo, San Pedro de Macorís is another favourite stop in Dominican Republic. No visit is complete without checking out El Parquecito, Patrimonio arquitectónico de la ciudad de San Pedro de Macoris and Museo Cultural San Pedro.

Plan the rest of your trip from Mexico City to Santo Domingo

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.